Introduction
Nobiletin is a polymethoxylated flavonoid compound extracted from the citrus peels of various fruits including the tangerine. A close chemical cousin of the well-studied tangeretin, nobiletin has potent anti-inflammatory, and anti-cancer properties. Due to its hydrophobic nature, nobiletin has been noted to have exceptional bioavailability in addition to blood brain barrier permeability. The latter is important for its novel anti-dementia, brain protective, and even nootropic characteristics.
